3 ms·

> it stops the virus from spreading "It doesn't fully stop spread, so it doesn't work as a whole". Thanks for giving another example for my comment.

fallingknife 5y ago
Most vaccines do fully stop the spread, even for measles, which is one of the most transmissible viruses known. So it's a reasonable standard.
- Uberphallus 5y ago
  > Most vaccines do fully stop the spread, even for measles, No, they don't. [0][1] From [1] > Two doses of MMR vaccine are about 97% effective at preventing measles; one dose is about 93% effective. Obviously those 3% and 7% do spread, even though the symptoms are milder. For the 97 and 93% ones there's indeed very limited (if any) shedding [3]. Now that's holding different bars, because asymptomatic measles infections are less contagious by themselves, regardless of vaccination status, unlike COVID-19 which is still relatively contagious while asymptomatic. So you're attributing a positive point of measles infections as a fault of the COVID-19 vaccines, which is, as you might see, a pretty misinformed take. Also, sterilizing immunity as you seem to understand doesn't really exist, in case that's the misconception you have [2]. In the end it's all about viral load, route of exposure, and level and type of immunity. A mucosal vaccine would behave more in the way your expecting intramuscular ones to work[4]. [0] https://academic.oup.com/cid/article/67/9/1315/5034094?login=true https://academic.oup.com/cid/article/67/9/1315/5034094?login... [1] https://www.cdc.gov/measles/vaccination.html https://www.cdc.gov/measles/vaccination.html [2] https://www.theatlantic.com/science/archive/2021/09/sterilizing-immunity-myth-covid-19-vaccines/620023/ https://www.theatlantic.com/science/archive/2021/09/steriliz... [3] https://academic.oup.com/jid/article/189/Supplement_1/S165/821757 https://academic.oup.com/jid/article/189/Supplement_1/S165/8... [4] https://www.nature.com/articles/s41577-021-00583-2 https://www.nature.com/articles/s41577-021-00583-2

fallingknife 5y ago

Most vaccines do fully stop the spread, even for measles, which is one of the most transmissible viruses known. So it's a reasonable standard.

Uberphallus 5y ago
> Most vaccines do fully stop the spread, even for measles, No, they don't. [0][1] From [1] > Two doses of MMR vaccine are about 97% effective at preventing measles; one dose is about 93% effective. Obviously those 3% and 7% do spread, even though the symptoms are milder. For the 97 and 93% ones there's indeed very limited (if any) shedding [3]. Now that's holding different bars, because asymptomatic measles infections are less contagious by themselves, regardless of vaccination status, unlike COVID-19 which is still relatively contagious while asymptomatic. So you're attributing a positive point of measles infections as a fault of the COVID-19 vaccines, which is, as you might see, a pretty misinformed take. Also, sterilizing immunity as you seem to understand doesn't really exist, in case that's the misconception you have [2]. In the end it's all about viral load, route of exposure, and level and type of immunity. A mucosal vaccine would behave more in the way your expecting intramuscular ones to work[4]. [0] https://academic.oup.com/cid/article/67/9/1315/5034094?login=true https://academic.oup.com/cid/article/67/9/1315/5034094?login... [1] https://www.cdc.gov/measles/vaccination.html https://www.cdc.gov/measles/vaccination.html [2] https://www.theatlantic.com/science/archive/2021/09/sterilizing-immunity-myth-covid-19-vaccines/620023/ https://www.theatlantic.com/science/archive/2021/09/steriliz... [3] https://academic.oup.com/jid/article/189/Supplement_1/S165/821757 https://academic.oup.com/jid/article/189/Supplement_1/S165/8... [4] https://www.nature.com/articles/s41577-021-00583-2 https://www.nature.com/articles/s41577-021-00583-2