4 ms·
"Next, the researchers delivered irisin directly into the mice’s brains." That sentence is not giving me much hope that they expect the hormone to survive dige
by captainbland 5y ago
"Next, the researchers delivered irisin directly into the mice’s brains."
That sentence is not giving me much hope that they expect the hormone to survive digestion.
- serrel 5y agoOnce it's in the bloodstream, the hormone passes the blood brain barrier. "In addition, the researchers found that irisin could cross the blood-brain barrier to act on the brain."
- heavyset_go 5y agoI'm not advocating for it, but there are ways to bypass first-pass metabolism or to get certain compounds or proteins through the blood-brain barrier.