"Past studies found that exercise induces production of FNDC5, a protein found on the surfaces of certain cells. FNDC5 can activate neuroprotective genes in the

"Past studies found that exercise induces production of FNDC5, a protein found on the surfaces of certain cells. FNDC5 can activate neuroprotective genes in the hippocampus, the brain region in charge of memory formation. The outer part of FNDC5 can be cleaved off to form a hormone called irisin, which is released into the bloodstream." see also https://pubmed.ncbi.nlm.nih.gov/25952527/ https://pubmed.ncbi.nlm.nih.gov/25952527/ "Irisin, as a new hormone-like myokine, is discovered in the presence of exercise-induced peroxisome proliferator-activated receptor gamma coactivator-1-alpha (PGC-1α)." https://en.wikipedia.org/wiki/FNDC5 https://en.wikipedia.org/wiki/FNDC5