I do this with two mice (well, one mouse and a trackpad). I had pretty bad repetitive strain in my right wrist. I realized it kicks in after using the mouse fo

I do this with two mice (well, one mouse and a trackpad). I had pretty bad repetitive strain in my right wrist. I realized it kicks in after using the mouse for too long. So now when I feel my right wrist start to complain (every few minutes) I just switch to the trackpad with my left hand. It also helps a ton to just learn keyboard shortcuts for everything.