3 ms·

Are you sure about that? https://www.nejm.org/doi/full/10.1056/nejmoa2007764 https://www.nejm.org/doi/full/10.1056/nejmoa2007764

• programmarchy 5y ago
  No, I don't think anyone is, because there are also studies that show no benefit: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099%2821%2900485-0/fulltext https://www.thelancet.com/journals/laninf/article/PIIS1473-3... However, I've also heard there's a new study coming out from Gilead that demonstrates Remdesivir is highly effective when administered in early treatment. So perhaps the efficacy depends when treatment is given. And if that's the case, then meta-studies actually become very important, because they can reveal hidden factors like dosage, demographic, when to administer treatment, etc.
  • thehappypm 5y ago
    The problem with Remdesivir is that it's often administered way, way too late. If someone's oxygen is at <90% and they're about to need a ventilator, there's already so much viruses in their system, so much inflammation, and so much cell death that stopping new viral reproduction is too little, too late.