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TLDR for the paper: GoF is not necessarily the strongest candidate for this flu outbreak. However, all the candidates are man-made due to research efforts. To
by gregwebs 5y ago
TLDR for the paper: GoF is not necessarily the strongest candidate for this flu outbreak. However, all the candidates are man-made due to research efforts.
To me this points out that every study on a pandemic-possible virus should have an extremely high bar to meet in terms of both safety and reason for performing the study in the first place. Effectively the only reason that is needed now to perform such research is that you want to publish a paper. The linked paper points out one possible source of the flu pandemic: vaccine development. This may have been a worthy enough cause but greater safeguards are needed. We should take the money we spend on GoF research and spend it on ensuring better safeguards for existing research.
GoF research has an explicit goal is to make a virus more human transmissible: if it is too successful, you end up with the possibility of a pandemic. We now have a COVID pandemic that might have been caused by GoF research. On the flip side we can't show much benefit from this kind of research.
- indymike 5y ago> On the flip side we can't show much benefit from this kind of research. In many ways GoF seems to bee like a site reliability team's "dynamite monkey Friday" where they try to break things in staging in unpredictable ways... hoping whatever they do to our staging environment doesn't leak to production. Fortunately, our app is not likey to cause bodily harm to anyone and not likely to cause a pandemic.