Both are safe options job wise. With python/Django it is going to be easier to land a backend position, where you will be using Django mostly for building APIS

Both are safe options job wise. With python/Django it is going to be easier to land a backend position, where you will be using Django mostly for building APIS and interacting with databases and third party systems and it will be less likely you will be expected to do frontend related stuff. Sadly not many companies nowadays do frontend with Django anymore, even if it were the right tool for the job, it is unfashionable to not do SPAs in most companies. With node, it will be easier to land on a position where you're more "full stack" and expected to also know css, html and more frontendy stuff.