4 ms·
Among other differences, Moderna dosages had ~3x more mRNA compared to Pfizer (100 v 30 micrograms), and their regime had longer periods between dosages. Appare
by ayngg 5y ago
Among other differences, Moderna dosages had ~3x more mRNA compared to Pfizer (100 v 30 micrograms), and their regime had longer periods between dosages. Apparently rationale for Pfizer doses was to minimize side effects because from their initial testing they did not find a significant increase in antibodies with a higher dosage [1].
[1] https://www.nejm.org/doi/full/10.1056/NEJMoa2027906 https://www.nejm.org/doi/full/10.1056/NEJMoa2027906