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Is there an archive link to the second article? The conclusion is not available... I find the premise interesting, but consider how many supplements/drugs inte
by lend000 5y ago
Is there an archive link to the second article? The conclusion is not available...
I find the premise interesting, but consider how many supplements/drugs intentionally inhibit MAO's at much higher than ng/L quantities and how promising they seem for Parkinson's (there seem to be more positive studies than negative studies, though the measured effect in both types tends to be quite small). It seems unlikely to be the critical factor determining health effects in alcoholic beverages.
- smichel17 5y agohttps://www.sci-hub.ru/https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1530-0277.1988.tb00264.x https://www.sci-hub.ru/https://onlinelibrary.wiley.com/doi/a...
- lend000 5y agoThanks. Their conclusion: "The contribution of harman in alcoholic beverages to the overall pharmacological and/or toxicological effects of the amine and its relationship to alcoholism needs to be investigated."
- eurasiantiger 5y agoAnd this would be that investigation, from 1996! https://pubmed.ncbi.nlm.nih.gov/8651457/ https://pubmed.ncbi.nlm.nih.gov/8651457/
- ProjectArcturis 5y agoJust once, I'd like to read a scientific paper that concludes, "We have completed study of this field. No further research is necessary."
- popcube 5y agolung cancer and cigarette
- eurasiantiger 5y agoNot by a long shot. The average person still thinks the culprit is nicotine, when nicotine is rather harmless compared to the addictiveness of concommittantly administered Harmala alkaloids, and to the damage caused by inhaling nano-/microparticulate matter and hot combustion gases.
- eurasiantiger 5y agoA lot of things inhibit the monoamine oxidases, but not that many things inhibit them at such small quantities, implying that these Harmala alkaloids are exceptionally bioactive.