Thinking about this a bit more, I could also imagine that cell state could not only be encoded in the cell proteome, phosphoproteome etc, but also in the set of

Thinking about this a bit more, I could also imagine that cell state could not only be encoded in the cell proteome, phosphoproteome etc, but also in the set of already activated (primed) receptors on the cell, so that the final signal only gets sent in cells that have been appropriately primed.