3 ms·

Rather than just posing an open ended conspiratorial hypothesis that has no evidence (it is trivial for anyone to get hold of a vial and sequence the mRNA to ac

Rather than just posing an open ended conspiratorial hypothesis that has no evidence (it is trivial for anyone to get hold of a vial and sequence the mRNA to actually test your absurd hypothesis) do you have a proposed endgame for ‘custom mRNAs’ to what must be a vast conspiracy involving thousands of scientists?

platonis 5y ago
You don't have to involve them, just insert custom sequences with defined purposes mixed with the real vaccine. I am not saying it's happening but don't you think it's a bit odd to see such a big push for a vaccine and not for other proven strategies such preventing vit D deficiency and giving NAC to decrease oxidative stress? The directive seems to be to vaccinate the entire population, not to prevent deaths.
robbiep 5y ago
In reply to your dead answer: Your hypothesis is falsafiable, and has been falsified. It's conspiratorial thinking, plain and simple. [0], [1] No, I do not think it is strange that Vit D and NAC are not under a 'huge push'. The UK made Vit D supplementation available for free last year and the NICE guidelines concluded that there was insufficient evidence at present to support global supplementation [2]. On NAC, there have been a number of small studies but no widespread studies of high quality so neither has made it into regular protocols. That's not to say they won't have some effect, but that the level of evidence to support their widespread usage is not available at present. Here's what I think is a better question: Why aim for something that either requires high compliance (regular Vit D supplementation, which motivated people can do for cents a day anyway) or pre-intubation Rx (NAC) when you can reduce the risk of hospitalisation (even against delta) or death by 80% with a free, widely available (in some countries), safe vaccine? It's simply clutching at straws [0] https://www.the-scientist.com/news-opinion/scientists-reverse-engineer-mrna-sequence-of-moderna-vaccine-68640 https://www.the-scientist.com/news-opinion/scientists-revers... [1] https://www.theguardian.com/world/2021/mar/30/university-scientists-deconstruct-covid-19-vaccines-and-publish-recipe-on-open-web https://www.theguardian.com/world/2021/mar/30/university-sci... [2] https://www.thelancet.com/journals/landia/article/PIIS2213-8587(21)00003-6/fulltext https://www.thelancet.com/journals/landia/article/PIIS2213-8...

platonis 5y ago

You don't have to involve them, just insert custom sequences with defined purposes mixed with the real vaccine. I am not saying it's happening but don't you think it's a bit odd to see such a big push for a vaccine and not for other proven strategies such preventing vit D deficiency and giving NAC to decrease oxidative stress? The directive seems to be to vaccinate the entire population, not to prevent deaths.

robbiep 5y ago

In reply to your dead answer: Your hypothesis is falsafiable, and has been falsified. It's conspiratorial thinking, plain and simple. [0], [1] No, I do not think it is strange that Vit D and NAC are not under a 'huge push'. The UK made Vit D supplementation available for free last year and the NICE guidelines concluded that there was insufficient evidence at present to support global supplementation [2]. On NAC, there have been a number of small studies but no widespread studies of high quality so neither has made it into regular protocols. That's not to say they won't have some effect, but that the level of evidence to support their widespread usage is not available at present. Here's what I think is a better question: Why aim for something that either requires high compliance (regular Vit D supplementation, which motivated people can do for cents a day anyway) or pre-intubation Rx (NAC) when you can reduce the risk of hospitalisation (even against delta) or death by 80% with a free, widely available (in some countries), safe vaccine? It's simply clutching at straws [0] https://www.the-scientist.com/news-opinion/scientists-reverse-engineer-mrna-sequence-of-moderna-vaccine-68640 https://www.the-scientist.com/news-opinion/scientists-revers... [1] https://www.theguardian.com/world/2021/mar/30/university-scientists-deconstruct-covid-19-vaccines-and-publish-recipe-on-open-web https://www.theguardian.com/world/2021/mar/30/university-sci... [2] https://www.thelancet.com/journals/landia/article/PIIS2213-8587(21)00003-6/fulltext https://www.thelancet.com/journals/landia/article/PIIS2213-8...