> For me I had with pandas the most issues using it's multiindex. Yessss. I loathe indices, and have never been in a situation where I was better off with them

> For me I had with pandas the most issues using it's multiindex. Yessss. I loathe indices, and have never been in a situation where I was better off with them than without them. > Regarding fast you have something like Vaex on python sid I've never used Vaex, but I've used datatable (https://github.com/h2oai/datatable https://github.com/h2oai/datatable) and polars (https://github.com/pola-rs/polars https://github.com/pola-rs/polars). Polars is my favorite API, but datatable was faster at reading data (Polars was faster in execution). I'll have to give Vaex a try at some point.