Yes, there are differences that seem unlikely to arise as part of natural evolution. There are also differences that seem unlikely to arise as part of a lab exp

Yes, there are differences that seem unlikely to arise as part of natural evolution. There are also differences that seem unlikely to arise as part of a lab experiment (i.e. things that are well beyond our known or predictable ability). Some kind of unlikely event still managed to happen. Treating the statistical improbability as evidence for only one conclusion is suspect.