4 ms·
Social reward learning starts very early in life. It's quite a claim that MDMA can overcome patterns ingrained during many years. It would have a major effect.
by tgv 5y ago
Social reward learning starts very early in life. It's quite a claim that MDMA can overcome patterns ingrained during many years. It would have a major effect. But then why wouldn't it work in another setting? It's not as if time is terribly critical: "the MDMA dose did indeed reopen the critical period for social reward learning in the adult mice, beginning around 6 to 48 hours after the dose. The reopening of the critical period lasted at least two weeks, up to around 4 weeks before returning to baseline." The mechanism proposed in the article, basically serotonin, would also affect more than just social reward learning, so how come there's no sign of that? I don't know the target audience of analyticalcannabis.com, but I would need to see much more evidence before writing such a positively worded article.
- mistermann 5y ago> But then why wouldn't it work in another setting? Is this referring to something explicit? I'd think it's certainly possible it could work in many, but only certain settings have been or can be studied, for specific definitions of "study".
- tpm 5y agoWell MDMA and other psychedelics do have major effects. I think the ultimate source of the article's claims is this study, but there might be others I am not aware of - the research of psychedelics has exploded lately. https://pubmed.ncbi.nlm.nih.gov/30944474/ https://pubmed.ncbi.nlm.nih.gov/30944474/