It's tempting to look at vaccinated/unvaccinated as a perfect RCT and the unvaccinated are a control group. This clearly isn't the case. There are surely many c

It's tempting to look at vaccinated/unvaccinated as a perfect RCT and the unvaccinated are a control group. This clearly isn't the case. There are surely many confounders at play. Looking at this release's underlying report they mention: "The age-adjusted mortality rate among unvaccinated individuals was 5.00 cases per 100,000 unvaccinated population and the age-adjusted mortality rate among vaccinated individuals was 0.33 per 100,000 vaccinated individuals for the four-week period ending August 28, 2021." So the difference in mortality rate is roughly ~5 in 100,000 of the population. This is a very low number. Does it obviously override any possible confounders to indicate a strong signal? Also remember this is age-adjusted. I would imagine this difference is substantially smaller for cohorts omitting the elderly. Is there a material benefit to younger reasonably healthy people? It seems the question is muddier than is typically made out.