4 ms·

A 6% false positive rate? You don't want anyone taking this without probable cause then, else you're going to get a metric crap-ton of people going to their doc

A 6% false positive rate? You don't want anyone taking this without probable cause then, else you're going to get a metric crap-ton of people going to their doctor's and having to have a full workup done. Edit to clarify: My point was that just because it was cheap doesn't mean it'll ever be sold to the public. Apart from anything else, consider the psychological impact of discovering you (may) have HIV from a test kit you picked up from next to the Oreos on a whim.

d0ne 15y ago
If you do some searching around you will find 3% to 5% false positive for blood test is not uncommon.
raganwald 15y ago
This is true of most tests. When he likelihood of a false positive is significant in relation to the expected incidence, you need corroboration such as symptoms developing before choosing to run the tests. Sidebar: This is misunderstood by people criticizing doctors who refuse to run tests without corroborating evidence. It's not just the money/scarce resources, it's the problem of false positives dominating actual positives.
jcoder 15y ago
Of course at $1/15m/test, a battery of tests is practically built in to the price. If the instructions are to "take three cards and put a drop of blood on each," and that it isn't a positive result unless all three agree, you've solved that problem.
- carbocation 15y ago
  Works for medical professionals, but I think to sell this to the general public, those three cards should be baked in together to avoid confusion.
  - danvet 15y ago
    Highly unlikely that three runs of the same test are fully independant, i.e. they might match all on the same antibody which is similar to an HIV one but not due to a HIV. You likely only prevent operation goof-ups like "oops, spilled a bit of blood from the needle of my bro here ..." (or something less fancy and more likely). Which is why in practice you run a different test to confirm results.
gus_massa 15y ago
Wikipedia says that the false positive rate of the standard ELISA test is only 1.5% (thats < 6%) http://en.wikipedia.org/wiki/HIV_test#Accuracy_of_HIV_testing http://en.wikipedia.org/wiki/HIV_test#Accuracy_of_HIV_testin... and a "positive" result should be confirmed by a Western Blot test. http://en.wikipedia.org/wiki/HIV_test#Interpreting_antibody_tests http://en.wikipedia.org/wiki/HIV_test#Interpreting_antibody_...

d0ne 15y ago

If you do some searching around you will find 3% to 5% false positive for blood test is not uncommon.

raganwald 15y ago

This is true of most tests. When he likelihood of a false positive is significant in relation to the expected incidence, you need corroboration such as symptoms developing before choosing to run the tests. Sidebar: This is misunderstood by people criticizing doctors who refuse to run tests without corroborating evidence. It's not just the money/scarce resources, it's the problem of false positives dominating actual positives.

jcoder 15y ago

Of course at $1/15m/test, a battery of tests is practically built in to the price. If the instructions are to "take three cards and put a drop of blood on each," and that it isn't a positive result unless all three agree, you've solved that problem.

carbocation 15y ago
Works for medical professionals, but I think to sell this to the general public, those three cards should be baked in together to avoid confusion.
- danvet 15y ago
  Highly unlikely that three runs of the same test are fully independant, i.e. they might match all on the same antibody which is similar to an HIV one but not due to a HIV. You likely only prevent operation goof-ups like "oops, spilled a bit of blood from the needle of my bro here ..." (or something less fancy and more likely). Which is why in practice you run a different test to confirm results.

gus_massa 15y ago

Wikipedia says that the false positive rate of the standard ELISA test is only 1.5% (thats < 6%) http://en.wikipedia.org/wiki/HIV_test#Accuracy_of_HIV_testing http://en.wikipedia.org/wiki/HIV_test#Accuracy_of_HIV_testin... and a "positive" result should be confirmed by a Western Blot test. http://en.wikipedia.org/wiki/HIV_test#Interpreting_antibody_tests http://en.wikipedia.org/wiki/HIV_test#Interpreting_antibody_...