>I think it probably will be endemic but we’re minimum scenario 3 I think the variables are: 1. Vaccine that prevents infection/transmission at a significantl

>I think it probably will be endemic but we’re minimum scenario 3 I think the variables are: 1. Vaccine that prevents infection/transmission at a significantly more substantial rate 2. Significant waning of vaccine effectiveness per new variants 3. Unexpected increase (or decrease) in virulence of new strains. 4. Significant improvements in treatment (including medications) These are, of course, unknowns. But, holding these constant, I believe we can calculate with fair accuracy how bad it will be as a direct function of the percentage of the population that's vaccinated.