There's a bunch of projects that have implemented this. I wrote a SQLite VFS in Go that lets you query a read-only SQLite db over http (including from s3) [0].

There's a bunch of projects that have implemented this. I wrote a SQLite VFS in Go that lets you query a read-only SQLite db over http (including from s3) [0]. The VFS API offers the possibility for weirder storage solutions, if thats the type of thing you're into. Recently I've been moving some of my personal websites hosted on AWS Lambda over to use a read/write sqlite db backed by DynamoDB[1]. There are a bunch of limitations to this type of thing (like it uses a global write lock), but it works nicely for DBs that have low write frequency. [0]: https://github.com/psanford/sqlite3vfshttp https://github.com/psanford/sqlite3vfshttp [1]: https://github.com/psanford/donutdb https://github.com/psanford/donutdb