8 ms·

What do you mean everyone? BC, Canada and Israel have some of the highest vaccination rates in the world. Yet cases continue to rise and restrictions are gettin

by 650 5y ago

What do you mean everyone? BC, Canada and Israel have some of the highest vaccination rates in the world. Yet cases continue to rise and restrictions are getting tighter.

graeme 5y ago
And as I wrote in my initial post, it is summer. This is the easy time!
lamontcg 5y ago
What do you mean what do I mean by everyone? I MEAN EVERYONE https://i.imgur.com/fTTBLia.gif https://i.imgur.com/fTTBLia.gif 100%, Including kids under-12. The one thing delta really changed was that we're all either getting vaccinated or getting infected and recovering. What we're doing now is dragging it out while the virus burns through the unvaccinated population still trying to flatten the curve to keep the hospitals from getting knocked over. We could have no restrictions tomorrow if everyone were fully vaccinated today.
- mythrwy 5y ago
  That's an incredible claim which I disbelieve. First of all, there will be no 100% vaccination globally. Second of all, variants will continue to emerge while we play wack a mole. Yes, in the vaccinated. Never mind potential animal reservoirs.
  - lamontcg 5y ago
    You actually don't mean variants you mean a future new strain that achieves escape mutation. That won't escape T-cells recognition to the currently circulating strain of the virus. Once everyone is vaccinated or recovered the disease burden of any future strain will go down by an order of magnitude at least. This is what happened with H1N1 which became endemic as simply seasonal influenza. After being displaced in 1957 by H2N2 it circulated in pigs for 50 years before jumping back into humans in 2009 -- but people born before 1957 still had cross-reactive T-cell immunity to the H1 protein of that virus. Existing human coronaviruses now just cause the common cold, even though HCoV-OC43 may have caused the last great pandemic of the 19th century with the 1889 pandemic. These respiratory pandemics all burn out as they transition to endemic spread and nearly everyone gains cross-reactive immunity to future strains.
    - mythrwy 5y ago
      No, I mean variants. That's a lot of claims.
      - lamontcg 5y ago
        Immunity to Pre-1950 H1N1 Influenza Viruses Confers Cross-Protection against the Pandemic Swine-Origin 2009 A (H1N1) Influenza Virus https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457446/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457446/ Complete Genomic Sequence of Human Coronavirus OC43: Molecular Clock Analysis Suggests a Relatively Recent Zoonotic Coronavirus Transmission Event https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544107/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544107/
- josephcsible 5y ago
  > We could have no restrictions tomorrow if everyone were fully vaccinated today. I believed this for the 2 months or so that mask mandates and other restrictions only applied to people who weren't fully vaccinated.

by 650 5y ago

What do you mean everyone? BC, Canada and Israel have some of the highest vaccination rates in the world. Yet cases continue to rise and restrictions are getting tighter.

graeme 5y ago

And as I wrote in my initial post, it is summer. This is the easy time!

lamontcg 5y ago

What do you mean what do I mean by everyone? I MEAN EVERYONE https://i.imgur.com/fTTBLia.gif https://i.imgur.com/fTTBLia.gif 100%, Including kids under-12. The one thing delta really changed was that we're all either getting vaccinated or getting infected and recovering. What we're doing now is dragging it out while the virus burns through the unvaccinated population still trying to flatten the curve to keep the hospitals from getting knocked over. We could have no restrictions tomorrow if everyone were fully vaccinated today.

mythrwy 5y ago
That's an incredible claim which I disbelieve. First of all, there will be no 100% vaccination globally. Second of all, variants will continue to emerge while we play wack a mole. Yes, in the vaccinated. Never mind potential animal reservoirs.
- lamontcg 5y ago
  You actually don't mean variants you mean a future new strain that achieves escape mutation. That won't escape T-cells recognition to the currently circulating strain of the virus. Once everyone is vaccinated or recovered the disease burden of any future strain will go down by an order of magnitude at least. This is what happened with H1N1 which became endemic as simply seasonal influenza. After being displaced in 1957 by H2N2 it circulated in pigs for 50 years before jumping back into humans in 2009 -- but people born before 1957 still had cross-reactive T-cell immunity to the H1 protein of that virus. Existing human coronaviruses now just cause the common cold, even though HCoV-OC43 may have caused the last great pandemic of the 19th century with the 1889 pandemic. These respiratory pandemics all burn out as they transition to endemic spread and nearly everyone gains cross-reactive immunity to future strains.
  - mythrwy 5y ago
    No, I mean variants. That's a lot of claims.
    - lamontcg 5y ago
      Immunity to Pre-1950 H1N1 Influenza Viruses Confers Cross-Protection against the Pandemic Swine-Origin 2009 A (H1N1) Influenza Virus https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457446/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457446/ Complete Genomic Sequence of Human Coronavirus OC43: Molecular Clock Analysis Suggests a Relatively Recent Zoonotic Coronavirus Transmission Event https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544107/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544107/
josephcsible 5y ago
> We could have no restrictions tomorrow if everyone were fully vaccinated today. I believed this for the 2 months or so that mask mandates and other restrictions only applied to people who weren't fully vaccinated.