3 ms·

According to the CDC (as of August 18th) there are at least 742 cases of myocarditis and myopericarditis associated with vaccination, potentially upwards of ~1,

According to the CDC (as of August 18th) there are at least 742 cases of myocarditis and myopericarditis associated with vaccination, potentially upwards of ~1,300 [1]. For males age 16-17 the reporting rate of myopericarditis after 2 doses of Pfizer is 71.5 per 1 million doses administered (0.0071%) [1]. For males aged 18-24 the reporting rate after 2 doses of Pfizer or Moderna is ~37 per 1 million doses (0.0037%). [1] https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2021-08-30/03-COVID-Su-508.pdf https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-...

walterbell 5y ago
Is slide #7 showing 20 times higher myopericarditis than baseline for 18-24 year old males?
thatsamonad 5y ago
Are these numbers higher or lower than what we’d expect to see in terms of myocarditis and myopericarditis cases resulting from infection with COVID-19? I’m genuinely curious as I haven’t been able to find a good comparison on my own but I have read that damage to heart tissue is a potential long-term complication resulting from natural infection.
- criticaltinker 5y ago
  Great question, I'm only aware of one paper that somewhat answers that question in a limited sub-population (college athletes). To truly answer that question we would need perform cardiac magnetic resonance imaging on a large population-representative sample. If anyone is aware of such a study please do share. > Representing 13 universities, cardiovascular testing was performed in 1597 athletes (964 men [60.4%]). Thirty-seven (including 27 men) were diagnosed with COVID-19 myocarditis (overall 2.3%; range per program, 0%-7.6%); 9 had clinical myocarditis and 28 had subclinical myocarditis. If cardiac testing was based on cardiac symptoms alone, only 5 athletes would have been detected (detected prevalence, 0.31%). Cardiac magnetic resonance imaging for all athletes yielded a 7.4-fold increase in detection of myocarditis (clinical and subclinical). Follow-up CMR imaging performed in 27 (73.0%) demonstrated resolution of T2 elevation in all (100%) and late gadolinium enhancement in 11 (40.7%). [1] Prevalence of Clinical and Subclinical Myocarditis in Competitive Athletes With Recent SARS-CoV-2 Infection https://jamanetwork.com/journals/jamacardiology/fullarticle/2780548 https://jamanetwork.com/journals/jamacardiology/fullarticle/...

walterbell 5y ago

Is slide #7 showing 20 times higher myopericarditis than baseline for 18-24 year old males?

thatsamonad 5y ago

Are these numbers higher or lower than what we’d expect to see in terms of myocarditis and myopericarditis cases resulting from infection with COVID-19? I’m genuinely curious as I haven’t been able to find a good comparison on my own but I have read that damage to heart tissue is a potential long-term complication resulting from natural infection.

criticaltinker 5y ago
Great question, I'm only aware of one paper that somewhat answers that question in a limited sub-population (college athletes). To truly answer that question we would need perform cardiac magnetic resonance imaging on a large population-representative sample. If anyone is aware of such a study please do share. > Representing 13 universities, cardiovascular testing was performed in 1597 athletes (964 men [60.4%]). Thirty-seven (including 27 men) were diagnosed with COVID-19 myocarditis (overall 2.3%; range per program, 0%-7.6%); 9 had clinical myocarditis and 28 had subclinical myocarditis. If cardiac testing was based on cardiac symptoms alone, only 5 athletes would have been detected (detected prevalence, 0.31%). Cardiac magnetic resonance imaging for all athletes yielded a 7.4-fold increase in detection of myocarditis (clinical and subclinical). Follow-up CMR imaging performed in 27 (73.0%) demonstrated resolution of T2 elevation in all (100%) and late gadolinium enhancement in 11 (40.7%). [1] Prevalence of Clinical and Subclinical Myocarditis in Competitive Athletes With Recent SARS-CoV-2 Infection https://jamanetwork.com/journals/jamacardiology/fullarticle/2780548 https://jamanetwork.com/journals/jamacardiology/fullarticle/...