3 ms·
There's a lot of literature on this, but you are quite right as there are tons of open questions. Some enhancer RNAs are non-functional. Others seem to help sta
by nextos 5y ago
There's a lot of literature on this, but you are quite right as there are tons of open questions. Some enhancer RNAs are non-functional. Others seem to help stabilizing chromosome contacts. Some do seem to encode secondary structures, so they are probably functional ncRNAs.
Irrespective of this, enhancer RNA transcription is very useful to track active regulatory regions and to perform QTL studies.