2 ms·

I think your points are valid, I see them as orthogonal to my comments. Just one remark: If part of the sodium intake is replaced with potassium, then chloride

• adrian_b 5y ago
  While what you say is correct, it is still better to use potassium supplements without chloride, because that gives you the freedom to adjust the sodium and potassium doses independently, without worrying about chloride. The daily requirements for sodium and chloride are strongly correlated, because their main use is to ensure correct concentrations of ions in the extracellular liquids, where sodium and chloride are the most abundant ions and they are used in proportional quantities. The main purpose of potassium is as as a positive ion in the intracellular liquids, needed to compensate the charge of the organic acids and phosphoric acid. Because of that, the quantity of potassium needed by the body is not correlated with the quantity of chloride needed, except weakly and indirectly, due to the normal range of ratios between the quantities of extracellular and intracellular liquids and the similar rates of renal losses.