2 ms·

The phase 1 study mentioned in this article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323835/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323835/ ("Dr.

by kitcar 5y ago

The phase 1 study mentioned in this article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323835/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323835/ ("Dr. Dedhar and colleagues previously identified a unique compound, known as SLC-0111—currently being evaluated in Phase 1 clinical trials—as a powerful inhibitor of the CAIX enzyme")

pella 5y ago
> known as SLC-0111 https://scholar.google.com/scholar?q=%22SLC-0111%22 https://scholar.google.com/scholar?q=%22SLC-0111%22 AND "U-104 (SLC-0111) is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki values of 45.1 nM and 4.5 nM, respectively. U-104 shows a significant delay in tumor growth in mice model. " For research use only. We do not sell to patients. 100 mg: EUR 292 https://www.medchemexpress.com/U-104.html https://www.medchemexpress.com/U-104.html