Another aspect that is missing from consideration is the element of time. Synthetic and natural dye will degrade or "patina" in different ways, over time and o

Another aspect that is missing from consideration is the element of time. Synthetic and natural dye will degrade or "patina" in different ways, over time and over the course of exposure to weathering, UV light, etc. In many cases the synthetic dye does not degrade at all, which for many use cases can be undesirable.