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That's what I've been proposing for a few months. Get the vaccine and then get the delta variant a few weeks later to crush it and then be super immune for futu

That's what I've been proposing for a few months. Get the vaccine and then get the delta variant a few weeks later to crush it and then be super immune for future variants that jet off of that one.

faeyanpiraat 5y ago
Do you have evidence that this is the best course of action?
- contravariant 5y ago
  Well the obvious problems with it is that it's hard to tell you've been infected and you need to quarantine for the entire duration until you are sure you've been infected and have recovered. Apart from that, if the protection from a vaccine is temporary then there's no reason to believe your immune system will learn anything from an infection it can already handle. That part of the immune response takes a while and may never succeed if the virus is long gone before then.
  - randomopining 5y ago
    The whole point of my strategy would be that perhaps Delta is a precursor to a, let's say, Zeta variant that has almost complete evasion to the vaccine. Let's say in January or something. So what you're doing is giving your body a high chance to crush the Delta and gain some cross-immunity towards the future evasive variant. Whereas if you just relied on the vaccine, it might not even work well in January. Obviously this is just conjecture, but I think a real possibility.
  - arisAlexis 5y ago
    Who knows if you getbDelta while vaccinated and you crush it shortly afternentry if your immune system makes any changes or not.. this requires an immunologist to answer.
Johnny555 5y ago
The vaccine is highly effective at preventing severe disease requiring hospitalization, but nothing is 100% (after 6 months, Pfizer is 97% effective at preventing severe disease) -- I'm not going to deliberately expose myself to something that could put me in a hospital. And no point, really. If I'm going to force myself to have the disease to build up immunity, why not just wait until I'm accidentally exposed (which may not happen)?
- randomopining 5y ago
  The whole point of my strategy would be that perhaps Delta is a precursor to a, let's say, Zeta variant that has almost complete evasion to the vaccine. Let's say in January or something. So what you're doing is giving your body a high chance to crush the Delta and gain some cross-immunity towards the future evasive variant. Whereas if you just relied on the vaccine, it might not even work well in January. Obviously this is just conjecture, but I think a real possibility.
  - Johnny555 5y ago
    Unless, of course, Zeta has almost complete evasion to natural immunity too. Then you've intentionally exposed yourself to Delta for no reason. I'll stick with my strategy of getting the vaccination (including a booster when eligible), and taking reasonable precautions against exposure.
    - randomopining 5y ago
      If it comes from the lineage of the prevalent strain... there's no way that it would not have cross-immunity after 6 months.

That's what I've been proposing for a few months. Get the vaccine and then get the delta variant a few weeks later to crush it and then be super immune for future variants that jet off of that one.

faeyanpiraat 5y ago

Do you have evidence that this is the best course of action?

contravariant 5y ago
Well the obvious problems with it is that it's hard to tell you've been infected and you need to quarantine for the entire duration until you are sure you've been infected and have recovered. Apart from that, if the protection from a vaccine is temporary then there's no reason to believe your immune system will learn anything from an infection it can already handle. That part of the immune response takes a while and may never succeed if the virus is long gone before then.
- randomopining 5y ago
  The whole point of my strategy would be that perhaps Delta is a precursor to a, let's say, Zeta variant that has almost complete evasion to the vaccine. Let's say in January or something. So what you're doing is giving your body a high chance to crush the Delta and gain some cross-immunity towards the future evasive variant. Whereas if you just relied on the vaccine, it might not even work well in January. Obviously this is just conjecture, but I think a real possibility.
- arisAlexis 5y ago
  Who knows if you getbDelta while vaccinated and you crush it shortly afternentry if your immune system makes any changes or not.. this requires an immunologist to answer.

Johnny555 5y ago

The vaccine is highly effective at preventing severe disease requiring hospitalization, but nothing is 100% (after 6 months, Pfizer is 97% effective at preventing severe disease) -- I'm not going to deliberately expose myself to something that could put me in a hospital. And no point, really. If I'm going to force myself to have the disease to build up immunity, why not just wait until I'm accidentally exposed (which may not happen)?

randomopining 5y ago
The whole point of my strategy would be that perhaps Delta is a precursor to a, let's say, Zeta variant that has almost complete evasion to the vaccine. Let's say in January or something. So what you're doing is giving your body a high chance to crush the Delta and gain some cross-immunity towards the future evasive variant. Whereas if you just relied on the vaccine, it might not even work well in January. Obviously this is just conjecture, but I think a real possibility.
- Johnny555 5y ago
  Unless, of course, Zeta has almost complete evasion to natural immunity too. Then you've intentionally exposed yourself to Delta for no reason. I'll stick with my strategy of getting the vaccination (including a booster when eligible), and taking reasonable precautions against exposure.
  - randomopining 5y ago
    If it comes from the lineage of the prevalent strain... there's no way that it would not have cross-immunity after 6 months.