3 ms·

it also generates immunity to the adenoviral vector proteins

• rolph 5y ago
  yes and this has been the big setback for many years this is why we dont have a lot of these vector vaccines. if someone is immune to adenovirus they typically destroy the vaccine before antigen can be presented. this reduces prophylactic opportunities regarding serial innoculation with adenovirus vector, regardless of the cassette load i am one of those people, having worked with adenovirus, as well as coronavirus, thus i am obligated to non adenoviral vaccine, and made out quite well during my infection with SARS-1, and with SARS-2
  • cblconfederate 5y ago
    you got infected with SARS1?
    • rolph 5y ago
      yes i did, when it was brand new, it was very concerning, i was very congested, labouring to breath and walking was starting to feel like running a marathon in 90 degree weather. when SARS-2 came around it was a case of the sniffles, with very high antibody titre, searching on a whim i discovered that i am not alone, and apparently SARS-1 convalesence related to outcome of SARS-2 infection