2 ms·
there is plenty of genetic evidence linking neanderthal genetic features to outcome of disease and genetic infirmity, as well as outcome of covid infection, pri
by rolph 5y ago
there is plenty of genetic evidence linking neanderthal genetic features to outcome of disease and genetic infirmity, as well as outcome of covid infection, primarily to do with interferon production and signaling, as well as receptor domains, these are heteroallelic as well, so strong neanderthal heritage with respect to population at large may provide a protective allele, or a predispositional allele.
https://www.sciencemag.org/news/2020/12/neanderthal-gene-found-many-people-may-open-cells-coronavirus-and-increase-covid-19 https://www.sciencemag.org/news/2020/12/neanderthal-gene-fou...
https://www.biorxiv.org/content/10.1101/2020.12.11.422139v1 https://www.biorxiv.org/content/10.1101/2020.12.11.422139v1
https://www.nature.com/articles/s41586-020-2818-3 https://www.nature.com/articles/s41586-020-2818-3
https://www.news-medical.net/news/20201215/Neanderthal-gene-variant-increases-risk-of-severe-COVID-19.aspx https://www.news-medical.net/news/20201215/Neanderthal-gene-...
https://www.nejm.org/doi/full/10.1056/NEJMe2025501 https://www.nejm.org/doi/full/10.1056/NEJMe2025501
https://www.pnas.org/content/118/9/e2026309118 https://www.pnas.org/content/118/9/e2026309118
https://www.biorxiv.org/content/10.1101/2020.12.11.422139v1 https://www.biorxiv.org/content/10.1101/2020.12.11.422139v1