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>antivax talking point (and for the most part a load of nonsense >>polio vaccine administered from 1955–1963 was contaminated with simian virus 40 (SV40). The

>antivax talking point (and for the most part a load of nonsense >>polio vaccine administered from 1955–1963 was contaminated with simian virus 40 (SV40). The virus came from the monkey kidney cell cultures used to produce the vaccine. Most, but not all, of the contamination was in the inactivated polio vaccine (IPV). Once the contamination was recognized, steps were taken to eliminate it from future vaccines. There have been many questions as to the effects on people who received the contaminated vaccine. SV40 has biological properties consistent with a cancer-causing virus, but researchers have not conclusively established whether or not it could cause cancer in humans. Studies of groups of people who received polio vaccine during 1955–1963 provide evidence of no increased cancer risk. >>However, because these epidemiologic studies are sufficiently flawed, the Institute of Medicine's Immunization Safety Review Committee concluded that the evidence was inadequate to conclude whether or not the contaminated polio vaccine caused cancer. In light of the biological evidence supporting the theory that SV40-contamination of polio vaccines could contribute to human cancers, the committee recommends continued public health attention in the form of policy analysis, communication, and targeted biological research. https://www.ncbi.nlm.nih.gov/books/NBK221112/ https://www.ncbi.nlm.nih.gov/books/NBK221112/ That sounds like a load of nonsense? >sciencebasedmedicine dot org >> This one popped up at that online repository of all things quackery, NaturalNews.com lol, pot, meet kettle. Why can't you trust the science? Simian virus 40 DNA sequences in human brain and bone tumours https://pubmed.ncbi.nlm.nih.gov/9776221/ https://pubmed.ncbi.nlm.nih.gov/9776221/ Sequence analyses of human tumor-associated SV40 DNAs and SV40 viral isolates from monkeys and humans https://pubmed.ncbi.nlm.nih.gov/9584955/ https://pubmed.ncbi.nlm.nih.gov/9584955/ Human cytomegalovirus major immediate early gene product can induce SV40 DNA replication in human embryonic lung cells https://pubmed.ncbi.nlm.nih.gov/2173262/ https://pubmed.ncbi.nlm.nih.gov/2173262/ Phylogenetic analysis of polyomavirus simian virus 40 from monkeys and humans reveals genetic variation https://pubmed.ncbi.nlm.nih.gov/15308725/ https://pubmed.ncbi.nlm.nih.gov/15308725/ SV40 DNA in human osteosarcomas shows sequence variation among T-antigen genes https://pubmed.ncbi.nlm.nih.gov/9311596/ https://pubmed.ncbi.nlm.nih.gov/9311596/ Natural simian virus 40 strains are present in human choroid plexus and ependymoma tumors https://pubmed.ncbi.nlm.nih.gov/7571441/ https://pubmed.ncbi.nlm.nih.gov/7571441/

foldr 5y ago
> https://www.ncbi.nlm.nih.gov/books/NBK221112/ https://www.ncbi.nlm.nih.gov/books/NBK221112/ > That sounds like a load of nonsense? "Based on these limitations, the committee concludes that the evidence is inadequate to accept or reject a causal relationship between SV40-containing polio vaccines and cancer." There is literally no reason to bring this up in relation to COVID vaccines. First, this was a contamination issue with polio vaccines between 1955 and 1961, long since fixed (and unlikely to happen again, as it is now much easier to detect this kind of contamination). Second, there has never been any good evidence that the 'contaminated' vaccines ever did anyone any harm.
- beerandt 5y ago
  You left out the ultimate conclusion: >In light of the biological evidence supporting the theory that SV40-contamination of polio vaccines could contribute to human cancers, the committee recommends continued public health attention in the form of policy analysis, communication, and targeted biological research. >long since fixed (and unlikely to happen again, as it is now much easier to detect this kind of contamination) Multiple vaccines have already been recalled due to contamination, after they passed initial qaqc. How does that make it unlikely that contaminated products don't go undetected? My point isn't that vaccine's shouldn't be taken. It's that the same people that constantly complain about pharmaceutical companies taking shortcuts and behaving unethically, suddenly decide the same companies are infallible when it comes to a rushed development of a product, from which they are fully shielded from liability. >There is literally no reason to bring this up in relation to COVID vaccines When someone suggests a concern is scifi conspiracy theory nonsense, and that concern has actually historically happened, then it's absolutely relevant. The scare tactics are bad enough, but don't try to trick people with lies and outright manipulation, and there won't be anything to call out.
  - foldr 5y ago
    >In light of the biological evidence supporting the theory that SV40-contamination of polio vaccines could contribute to human cancers, the committee recommends continued public health attention in the form of policy analysis, communication, and targeted biological research. Come on – this is just the standard ass-covering language in a scientific paper. "Further research is needed." By the nature of the case it's very hard to conclusively show that no-one has ever had a cancer caused by a 1960s Polio vaccine. But at present there is no good evidence that this has happened, as the paper that you linked to states very clearly. Any medication can contain contaminants. I do not understand why you think that the mere abstract possibility that any given vaccine might contain contaminants is relevant to COVID vaccination efforts. This is like cautioning against people taking Aspirin because any given Aspirin pill might contain contaminants.

foldr 5y ago

> https://www.ncbi.nlm.nih.gov/books/NBK221112/ https://www.ncbi.nlm.nih.gov/books/NBK221112/ > That sounds like a load of nonsense? "Based on these limitations, the committee concludes that the evidence is inadequate to accept or reject a causal relationship between SV40-containing polio vaccines and cancer." There is literally no reason to bring this up in relation to COVID vaccines. First, this was a contamination issue with polio vaccines between 1955 and 1961, long since fixed (and unlikely to happen again, as it is now much easier to detect this kind of contamination). Second, there has never been any good evidence that the 'contaminated' vaccines ever did anyone any harm.

beerandt 5y ago
You left out the ultimate conclusion: >In light of the biological evidence supporting the theory that SV40-contamination of polio vaccines could contribute to human cancers, the committee recommends continued public health attention in the form of policy analysis, communication, and targeted biological research. >long since fixed (and unlikely to happen again, as it is now much easier to detect this kind of contamination) Multiple vaccines have already been recalled due to contamination, after they passed initial qaqc. How does that make it unlikely that contaminated products don't go undetected? My point isn't that vaccine's shouldn't be taken. It's that the same people that constantly complain about pharmaceutical companies taking shortcuts and behaving unethically, suddenly decide the same companies are infallible when it comes to a rushed development of a product, from which they are fully shielded from liability. >There is literally no reason to bring this up in relation to COVID vaccines When someone suggests a concern is scifi conspiracy theory nonsense, and that concern has actually historically happened, then it's absolutely relevant. The scare tactics are bad enough, but don't try to trick people with lies and outright manipulation, and there won't be anything to call out.
- foldr 5y ago
  >In light of the biological evidence supporting the theory that SV40-contamination of polio vaccines could contribute to human cancers, the committee recommends continued public health attention in the form of policy analysis, communication, and targeted biological research. Come on – this is just the standard ass-covering language in a scientific paper. "Further research is needed." By the nature of the case it's very hard to conclusively show that no-one has ever had a cancer caused by a 1960s Polio vaccine. But at present there is no good evidence that this has happened, as the paper that you linked to states very clearly. Any medication can contain contaminants. I do not understand why you think that the mere abstract possibility that any given vaccine might contain contaminants is relevant to COVID vaccination efforts. This is like cautioning against people taking Aspirin because any given Aspirin pill might contain contaminants.