5 ms·

Why is it a vaccine? Are there going to be vaccine for everything in the future?

by Thaxll 5y ago

mschuster91 5y ago
> Are there going to be vaccine for everything in the future? For a lot of stuff, the answer is probably yes, mRNA based vaccines are a revolutionary game changer - their quick turnaround time means you can actually tailor them to a specific cancer or pathogen the patient has and use the patient's own immune system to fight against the disease. Another advantage of mRNA is that manufacture doesn't depend on chicken eggs which take about six months to produce, are challenging to keep sterile enough and have issues for people with allergies (https://edition.cnn.com/2020/03/27/health/chicken-egg-flu-vaccine-intl-hnk-scli/index.html https://edition.cnn.com/2020/03/27/health/chicken-egg-flu-va...). However, some viruses like HIV or Influenza mutate so much that it was hard to make effective viruses, we will have to wait and see what the future brings there.
dovebird 5y ago
Yes. The beauty of the Vaccine is that it sells on fear. And there is no limit to which a human being can be scared...
- mantas 5y ago
  Lyme is one of those disease where fear is valid to say the least.
mantas 5y ago
Because Lyme disease is hard to catch early. And long-lasting Lyme is damn hard to treat with lots of side effects.
Tycho 5y ago
I think thanks to Covid booster shots they realise they can pivot to a Vaccine-as-a-Service model and create all sorts of recurring revenue streams.
- cinntaile 5y ago
  Not really. They have been working on this Lyme disease vaccine since 2017.
foolinaround 5y ago
Should we have a vaccine for addictions? alcoholism? drug use? eating? Eg: Give it early in people's lives, that the first time they drink even a little alcohol, it should produce such (non life threatening) symptoms - terrible taste, throw up etc, they would not touch it again, and therefore won't be addicted?
- turbinerneiter 5y ago
  I had all those symptoms when I drank my first beer and still learned to love it. You can overcome everything if you really want to.
  - foolinaround 5y ago
    well, its not a strong enough signal then...
- twooster 5y ago
  It's been done: https://en.wikipedia.org/wiki/Disulfiram https://en.wikipedia.org/wiki/Disulfiram Not as a vaccine, but as a drug.
cinntaile 5y ago
Lets hope so, then we can prevent instead of treat :)
meibo 5y ago
Vaccines are a very good way to prevent serious disease and may make it possible to eradicate diseases. The best medical treatment is the one you never have to do.
- tboyd47 5y ago
  A vaccine is a medical treatment.
bregma 5y ago
A vaccine is an excellent way to prevent an infectious disease. Borelliosis is an infectious disease. Infectious diseases cause human suffering. Vaccinating against as many infectious diseases as possible will reduce a great deal of human suffering. I guess the real question is why would you not want to reduce human suffering?
Ensorceled 5y ago
Why wouldn't there be a vaccine? In Ontario, we give children vaccines for diphtheria, tetanus, pertussis, polio, influenza, smallpox (well, I got it as a child), rotavirus, IPD, measles, mumps, rubella, chickenpox, HPV, Hepatitis B, meningococcal disease. Ticks carrying Lyme disease are exploding in Ontario, probably because of climate change. It makes sense to get this into the rotation as soon as possible. After COVID, we suddenly have everybody is acting like vaccines are something weird, odd, new and scary.
- detaro 5y ago
  anthrax is a standard vaccination, really? that one seems kind of surprising.
  - Ensorceled 5y ago
    Oops. Started listing all vaccines and then took the response in a different direction. Deleted Anthrax.
    - nexuist 5y ago
      For the record, there is an anthrax vaccine at least in the US, but it is reserved for service members and politicians due to the potential for side effects. I believe we have a stockpile of a few million shots in the event of an outbreak, but that stuff is guarded by national security confidentiality so there's no way to know how prepared we really are.
      - Ensorceled 5y ago
        Yep. Active duty service in Canada get a shit load as well, all the stuff they already should have got as kids and at least Yellow Fever, Typhoid and, I think, Hep A.
- CountDrewku 5y ago
  >Ticks carrying Lyme disease are exploding in Ontario, probably because of climate change. Do you have proof of this?
triceratops 5y ago
> Are there going to be vaccine for everything in the future? We should be so lucky!
tboyd47 5y ago
Vaccines are for healthy people, so it's a larger market.
shusaku 5y ago
It’s because the human immune system is superb at fighting off disease, so it turns out it’s easier to just prime it than to create our own way to kill viruses.
exhilaration 5y ago
Imagine a vaccine against various cancers!
- M2Ys4U 5y ago
  Cancer is exactly why we vaccinate against HPV, as it's a huge cause of cervical cancer.
  - astura 5y ago
    HPV also causes vulva, vagina, penis, anus, and oropharynx cancers as well. https://www.cdc.gov/cancer/hpv/basic_info/cancers.htm https://www.cdc.gov/cancer/hpv/basic_info/cancers.htm >In general, HPV is thought to be responsible for more than 90% of anal and cervical cancers, about 70% of vaginal and vulvar cancers, and 60% of penile cancers. Cancers in the back of the throat (oropharynx) traditionally have been caused by tobacco and alcohol, but recent studies1 2 3 show that about 60% to 70% of cancers of the oropharynx may be linked to HPV. Many of these may be caused by a combination of tobacco, alcohol, and HPV.
- blackbear_ 5y ago
  People have been working on cancer vaccines for a long time actually, it's just so hard. - https://www.annualreviews.org/doi/10.1146/annurev-cancerbio-060820-111701 https://www.annualreviews.org/doi/10.1146/annurev-cancerbio-... - https://www.jimmunol.org/content/200/2/443 https://www.jimmunol.org/content/200/2/443 - https://science.sciencemag.org/content/359/6382/1355 https://science.sciencemag.org/content/359/6382/1355
- astura 5y ago
  No need to imagine, HPV infection causes cervical, vulva, vagina, penis, anus, and oropharynx cancer and we have a vaccine for HPV (that is effective against the majority of the strains of HPV that cause cancer)! According to the CDC "almost all cervical cancer can be prevented by HPV vaccination."

Why is it a vaccine? Are there going to be vaccine for everything in the future?

by Thaxll 5y ago

Why is it a vaccine? Are there going to be vaccine for everything in the future?

> Are there going to be vaccine for everything in the future? For a lot of stuff, the answer is probably yes, mRNA based vaccines are a revolutionary game changer - their quick turnaround time means you can actually tailor them to a specific cancer or pathogen the patient has and use the patient's own immune system to fight against the disease. Another advantage of mRNA is that manufacture doesn't depend on chicken eggs which take about six months to produce, are challenging to keep sterile enough and have issues for people with allergies (https://edition.cnn.com/2020/03/27/health/chicken-egg-flu-vaccine-intl-hnk-scli/index.html https://edition.cnn.com/2020/03/27/health/chicken-egg-flu-va...). However, some viruses like HIV or Influenza mutate so much that it was hard to make effective viruses, we will have to wait and see what the future brings there.

dovebird 5y ago

Yes. The beauty of the Vaccine is that it sells on fear. And there is no limit to which a human being can be scared...

mantas 5y ago
Lyme is one of those disease where fear is valid to say the least.

mantas 5y ago

Because Lyme disease is hard to catch early. And long-lasting Lyme is damn hard to treat with lots of side effects.

Tycho 5y ago

I think thanks to Covid booster shots they realise they can pivot to a Vaccine-as-a-Service model and create all sorts of recurring revenue streams.

cinntaile 5y ago
Not really. They have been working on this Lyme disease vaccine since 2017.

foolinaround 5y ago

Should we have a vaccine for addictions? alcoholism? drug use? eating? Eg: Give it early in people's lives, that the first time they drink even a little alcohol, it should produce such (non life threatening) symptoms - terrible taste, throw up etc, they would not touch it again, and therefore won't be addicted?

turbinerneiter 5y ago
I had all those symptoms when I drank my first beer and still learned to love it. You can overcome everything if you really want to.
- foolinaround 5y ago
  well, its not a strong enough signal then...
twooster 5y ago
It's been done: https://en.wikipedia.org/wiki/Disulfiram https://en.wikipedia.org/wiki/Disulfiram Not as a vaccine, but as a drug.

cinntaile 5y ago

Lets hope so, then we can prevent instead of treat :)

meibo 5y ago

Vaccines are a very good way to prevent serious disease and may make it possible to eradicate diseases. The best medical treatment is the one you never have to do.

tboyd47 5y ago
A vaccine is a medical treatment.

bregma 5y ago

A vaccine is an excellent way to prevent an infectious disease. Borelliosis is an infectious disease. Infectious diseases cause human suffering. Vaccinating against as many infectious diseases as possible will reduce a great deal of human suffering. I guess the real question is why would you not want to reduce human suffering?

Ensorceled 5y ago

Why wouldn't there be a vaccine? In Ontario, we give children vaccines for diphtheria, tetanus, pertussis, polio, influenza, smallpox (well, I got it as a child), rotavirus, IPD, measles, mumps, rubella, chickenpox, HPV, Hepatitis B, meningococcal disease. Ticks carrying Lyme disease are exploding in Ontario, probably because of climate change. It makes sense to get this into the rotation as soon as possible. After COVID, we suddenly have everybody is acting like vaccines are something weird, odd, new and scary.

detaro 5y ago
anthrax is a standard vaccination, really? that one seems kind of surprising.
- Ensorceled 5y ago
  Oops. Started listing all vaccines and then took the response in a different direction. Deleted Anthrax.
  - nexuist 5y ago
    For the record, there is an anthrax vaccine at least in the US, but it is reserved for service members and politicians due to the potential for side effects. I believe we have a stockpile of a few million shots in the event of an outbreak, but that stuff is guarded by national security confidentiality so there's no way to know how prepared we really are.
    - Ensorceled 5y ago
      Yep. Active duty service in Canada get a shit load as well, all the stuff they already should have got as kids and at least Yellow Fever, Typhoid and, I think, Hep A.
CountDrewku 5y ago
>Ticks carrying Lyme disease are exploding in Ontario, probably because of climate change. Do you have proof of this?

triceratops 5y ago

> Are there going to be vaccine for everything in the future? We should be so lucky!

tboyd47 5y ago

Vaccines are for healthy people, so it's a larger market.

shusaku 5y ago

It’s because the human immune system is superb at fighting off disease, so it turns out it’s easier to just prime it than to create our own way to kill viruses.

exhilaration 5y ago

Imagine a vaccine against various cancers!

M2Ys4U 5y ago
Cancer is exactly why we vaccinate against HPV, as it's a huge cause of cervical cancer.
- astura 5y ago
  HPV also causes vulva, vagina, penis, anus, and oropharynx cancers as well. https://www.cdc.gov/cancer/hpv/basic_info/cancers.htm https://www.cdc.gov/cancer/hpv/basic_info/cancers.htm >In general, HPV is thought to be responsible for more than 90% of anal and cervical cancers, about 70% of vaginal and vulvar cancers, and 60% of penile cancers. Cancers in the back of the throat (oropharynx) traditionally have been caused by tobacco and alcohol, but recent studies1 2 3 show that about 60% to 70% of cancers of the oropharynx may be linked to HPV. Many of these may be caused by a combination of tobacco, alcohol, and HPV.
blackbear_ 5y ago
People have been working on cancer vaccines for a long time actually, it's just so hard. - https://www.annualreviews.org/doi/10.1146/annurev-cancerbio-060820-111701 https://www.annualreviews.org/doi/10.1146/annurev-cancerbio-... - https://www.jimmunol.org/content/200/2/443 https://www.jimmunol.org/content/200/2/443 - https://science.sciencemag.org/content/359/6382/1355 https://science.sciencemag.org/content/359/6382/1355
astura 5y ago
No need to imagine, HPV infection causes cervical, vulva, vagina, penis, anus, and oropharynx cancer and we have a vaccine for HPV (that is effective against the majority of the strains of HPV that cause cancer)! According to the CDC "almost all cervical cancer can be prevented by HPV vaccination."