Some highlights from my notes on the OP [1]: > All anti-NTD neutralizing antibodies failed to recognize the Delta spike, indicating that the Delta variant is c

Some highlights from my notes on the OP [1]: > All anti-NTD neutralizing antibodies failed to recognize the Delta spike, indicating that the Delta variant is completely resistant to anti-NTD neutralizing antibodies elicited by wild-type spike protein, which is the antigenic component of widely used mRNA vaccines. > A third round of booster immunization with the SARS-CoV-2 vaccine is currently under consideration. Our data suggest that repeated immunization with the wild-type spike may not be effective in controlling the newly emerging Delta variants. [1] The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines https://www.biorxiv.org/content/10.1101/2021.08.22.457114v1 https://www.biorxiv.org/content/10.1101/2021.08.22.457114v1