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Yes this is a great point. The primary concerns & warnings are generally around vaccine induced immune escape, which is a realistic consequence of indiscriminat
by criticaltinker 5y ago
Yes this is a great point. The primary concerns & warnings are generally around vaccine induced immune escape, which is a realistic consequence of indiscriminate compulsory mass vaccination [1][2][3][4][5][6].
That said, there is general consensus in the literature that the vaccines are mostly safe for adults in the short term. However for certain sub-populations (eg pediatrics and pregnant women) there isn't enough evidence yet from clinical trials and longitudinal studies to conclude with certainty that the benefits of compulsory mass vaccination outweigh the risks.
[1] Risk of rapid evolutionary escape from biomedical interventions targeting SARS-CoV-2 spike protein
https://pubmed.ncbi.nlm.nih.gov/33909660/ https://pubmed.ncbi.nlm.nih.gov/33909660/
[2] Can we predict the limits of SARS-CoV-2 variants and their phenotypic consequences?
https://www.gov.uk/government/publications/long-term-evolution-of-sars-cov-2-26-july-2021 https://www.gov.uk/government/publications/long-term-evoluti...
[3] Why does drug resistance readily evolve but vaccine resistance does not?
https://royalsocietypublishing.org/doi/pdf/10.1098/rspb.2016.2562 https://royalsocietypublishing.org/doi/pdf/10.1098/rspb.2016...
[4] The adaptive evolution of virulence: a review of theoretical predictions and empirical tests
https://pubmed.ncbi.nlm.nih.gov/26302775/ https://pubmed.ncbi.nlm.nih.gov/26302775/
[5] Imperfect Vaccination Can Enhance the Transmission of Highly Virulent Pathogens
https://journals.plos.org/plosbiology/article?id=10.1371%2Fjournal.pbio.1002198 https://journals.plos.org/plosbiology/article?id=10.1371%2Fj...
[6] Necessity of COVID-19 vaccination in previously infected individuals
https://www.medrxiv.org/content/10.1101/2021.06.01.21258176v3.full.pdf https://www.medrxiv.org/content/10.1101/2021.06.01.21258176v...
- criticaltinker 5y agoLots of down-votes and no replies tells me this is striking some nerves - anyone care to articulate why you disagree with or do not support these statements?
- yupper32 5y agoAlmost no one on HN is qualified to take a group of medical journal articles/research papers and form an accurate opinion on the subject. In fact, trying to do so for most on this forum would probably result in inaccurate views due to misunderstanding the articles and papers. So people probably downvoted because you have a view on the subject, but no one is qualified to back or oppose it. And we don't know who you are, so how are we supposed to vet your view, or even begin to have a conversation about it? I didn't downvote (or upvote), but that's my guess.
- _flagged_ 5y agoIn that case almost all of the comments here should be downvoted or flagged.