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The US needs it if they want people who are spooked my mRNA tech to get vaccinated. They also need it if they want a vaccine that is the mostly likely to be saf

The US needs it if they want people who are spooked my mRNA tech to get vaccinated. They also need it if they want a vaccine that is the mostly likely to be safe for use in children.

ceejayoz 5y ago
The US has the J&J vaccine for that.
- giantg2 5y ago
  It's a similar mechanism, right? You're just using a virus to carry the genetic material, which also involves an extra transcription step in the cell (what is theorized as causing mutations in the spike and thus the stroke/clotting issues). Still quite different from the traditional inactive or protein based ones.
  - rrock 5y ago
    Transcription causes mutations in the spike that causes clotting issues? Do you have any idea how much transcription happens in your cells, every moment of every day? You need to reconsider where you’re getting your information.
    - giantg2 5y ago
      Here you go: https://www.euronews.com/next/2021/05/27/why-are-aztrazeneca-and-j-j-vaccines-causing-blood-clots-scientists-claim-they-have-the-an https://www.euronews.com/next/2021/05/27/why-are-aztrazeneca... https://www.europeanpharmaceuticalreview.com/news/155536/breaking-news-researchers-may-know-the-cause-for-covid-19-vaccine-related-blood-clots/ https://www.europeanpharmaceuticalreview.com/news/155536/bre...
giantg2 5y ago
There's the Novavax one. It's been in testing about as long as Pfizer and is US based. It hasn't been pushed along with the help of a larger partner like the others. Maybe they will get there. I would have preferred a vaccine using more traditional technology due to the lack of information on the potential for autoimmune conditions in the future.
doliveira 5y ago
That's assuming they're not going to find out yet another excuse. Both vector vaccines and inactivated virus vaccines have faced just as much opposition.
- whymauri 5y ago
  Yeah, people seem to be forgetting the anti-vaxx movement that was already brewing way before COVID.
  - pensatoio 5y ago
    The opposition to rushed or mandated COVID vaccination has close to zero ties to the “anti-vaccine” movement. Unless you watch CNN and MSNBC as your primary source of news, of course.
    - whymauri 5y ago
      if you don't think there's significant overlap I have a bridge to sell you In either case, while non-mRNA vaccines may incentive the 'vaccine hesitant' to get poked, no amount of modification or scientific advance will get anti-vaxxers to get immunized edit: with a vaccine (I'm assuming an FDA-approved small molecule therapeutic would be OK with some of them).
nl 5y ago
Astrazeneca and J&J are both non-mRNA vaccines.
- ibejoeb 5y ago
  AZ isn't available in the United States. OK, fine, it's not just mRNA. It's novel tech vs. well known tech like attenuated/inactivated virus. Beyond that, Covaxin is the only that I'm aware of that is performing well under delta.
  - enragedcacti 5y ago
    Pfizer is performing well under delta: https://www.covid-datascience.com/post/israeli-data-how-can-efficacy-vs-severe-disease-be-strong-when-60-of-hospitalized-are-vaccinated https://www.covid-datascience.com/post/israeli-data-how-can-...

The US needs it if they want people who are spooked my mRNA tech to get vaccinated. They also need it if they want a vaccine that is the mostly likely to be safe for use in children.

ceejayoz 5y ago

The US has the J&J vaccine for that.

giantg2 5y ago
It's a similar mechanism, right? You're just using a virus to carry the genetic material, which also involves an extra transcription step in the cell (what is theorized as causing mutations in the spike and thus the stroke/clotting issues). Still quite different from the traditional inactive or protein based ones.
- rrock 5y ago
  Transcription causes mutations in the spike that causes clotting issues? Do you have any idea how much transcription happens in your cells, every moment of every day? You need to reconsider where you’re getting your information.
  - giantg2 5y ago
    Here you go: https://www.euronews.com/next/2021/05/27/why-are-aztrazeneca-and-j-j-vaccines-causing-blood-clots-scientists-claim-they-have-the-an https://www.euronews.com/next/2021/05/27/why-are-aztrazeneca... https://www.europeanpharmaceuticalreview.com/news/155536/breaking-news-researchers-may-know-the-cause-for-covid-19-vaccine-related-blood-clots/ https://www.europeanpharmaceuticalreview.com/news/155536/bre...

giantg2 5y ago

There's the Novavax one. It's been in testing about as long as Pfizer and is US based. It hasn't been pushed along with the help of a larger partner like the others. Maybe they will get there. I would have preferred a vaccine using more traditional technology due to the lack of information on the potential for autoimmune conditions in the future.

doliveira 5y ago

That's assuming they're not going to find out yet another excuse. Both vector vaccines and inactivated virus vaccines have faced just as much opposition.

whymauri 5y ago
Yeah, people seem to be forgetting the anti-vaxx movement that was already brewing way before COVID.
- pensatoio 5y ago
  The opposition to rushed or mandated COVID vaccination has close to zero ties to the “anti-vaccine” movement. Unless you watch CNN and MSNBC as your primary source of news, of course.
  - whymauri 5y ago
    if you don't think there's significant overlap I have a bridge to sell you In either case, while non-mRNA vaccines may incentive the 'vaccine hesitant' to get poked, no amount of modification or scientific advance will get anti-vaxxers to get immunized edit: with a vaccine (I'm assuming an FDA-approved small molecule therapeutic would be OK with some of them).

nl 5y ago

Astrazeneca and J&J are both non-mRNA vaccines.

ibejoeb 5y ago
AZ isn't available in the United States. OK, fine, it's not just mRNA. It's novel tech vs. well known tech like attenuated/inactivated virus. Beyond that, Covaxin is the only that I'm aware of that is performing well under delta.
- enragedcacti 5y ago
  Pfizer is performing well under delta: https://www.covid-datascience.com/post/israeli-data-how-can-efficacy-vs-severe-disease-be-strong-when-60-of-hospitalized-are-vaccinated https://www.covid-datascience.com/post/israeli-data-how-can-...