This is commonly called the 'Paradoxical Reaction' and is pretty well documented, not just for stimulants. Antihistamines, for example, may cause drowsiness in

This is commonly called the 'Paradoxical Reaction' and is pretty well documented, not just for stimulants. Antihistamines, for example, may cause drowsiness in neurotypicals but increased agitation & activity in ADHD. Per my ADHD sister, she's supposed to inform her anesthesiologist of this prior to any surgeries because there's similar complications with some anesthesia.