3 ms·
One more link that tries to collect current clinical trials: https://www.lifespan.io/road-maps/the-rejuvenation-roadmap/ https://www.lifespan.io/road-maps/the-r
by xiphias2 5y ago
One more link that tries to collect current clinical trials: https://www.lifespan.io/road-maps/the-rejuvenation-roadmap/ https://www.lifespan.io/road-maps/the-rejuvenation-roadmap/
And an example for success for treating mitochondrial disease: https://www.lifespan.io/road-maps/the-rejuvenation-roadmap/gensight-biologics-gs010-lumevoq https://www.lifespan.io/road-maps/the-rejuvenation-roadmap/g...
https://www.gensight-biologics.com/product/gs010-for-lhon/ https://www.gensight-biologics.com/product/gs010-for-lhon/
Sure, it's not moving mitochondrial DNA to Nucleus directly, but the vector allows a specific mitochondrial gene to be expressed inside the nucleus. In the future base / prime editing (which didn't exist 10 years ago) can be used to fix mitochondrial DNA damage, which is probably much better solution: https://www.nature.com/articles/d41586-020-02054-5 https://www.nature.com/articles/d41586-020-02054-5
So far the car maintainence metaphore of curing aging seems right.