Good point. As I said, it may be fallacious reasoning on my part :) I suppose what this underscores is: biology is immensely complex and first-principles think

Good point. As I said, it may be fallacious reasoning on my part :) I suppose what this underscores is: biology is immensely complex and first-principles thinking can only get you so far. Eventually, you need to test things with a big RCT to know what's going on.