Sorry for not mentioning both, i consider both part of the feedback loop.I considered ghrelin a tad more important because of two things. If a stomach is extend

Sorry for not mentioning both, i consider both part of the feedback loop.I considered ghrelin a tad more important because of two things. If a stomach is extended(can grow to 7 times it's size) , the ghrelin feedback is temporarily not synchronized and will trigger appetite and hunger pangs more frequent and the leptin cannot counterbalance this too well. The other point is, everyone knows that feeling, after some hefty Chinese meal or mc Donald's, even though plenty calories have been consumed, 30minutes later you feel like "having an extra". The ghrelin simply overrides the leptin reaction. Thanks for the addition, I have just always held the opinion that ghrelin has more effects. Another example would be on a binge, no matter if people eat slow or fast(important for leptin trigger), the appetite keeps being a bit higher than the satiety sensation for some reason. Btw, I wanted to add that I did not intend to just point fingers at the US, was just because the title is us centric. Europe is mostly no better, nor are most LATAM countries.