Not really. As long as you've got a grid of pixels, it doesn't much matter what their shape is. Of course having a regular pixel sizing would end up with distor

Not really. As long as you've got a grid of pixels, it doesn't much matter what their shape is. Of course having a regular pixel sizing would end up with distorted images. Correcting for lens distortion isn't exactly a new trick, but if you want to be really fancy about it you could probably make non-uniform pixels too, correcting for it in hardware.