11 ms·

Are you referring to the theory that the severity of covid has a dose-response relationship with the infectious inoculum? It's an interesting theory, but I thin

Are you referring to the theory that the severity of covid has a dose-response relationship with the infectious inoculum? It's an interesting theory, but I think it is far from proven. It's a shame that it's not studied, because if true it might actually make sense to just give everyone a very small infectious inoculum as a form of vaccination.

kube-system 5y ago
The infectious dose of viruses is usually not (never?) a single particle. Depending on the virus, it may be tens or hundreds of particles required to infect a person. We don't know an exact number for COVID, but we know that it's likely some number that's greater than one. Whatever that number is, if we limit the number of particles in the air, we decrease the statistical probability that a person will come in contact to a number of particles exceeding that number. It's a "solution to pollution is dilution" issue. > it might actually make sense to just give everyone a very small infectious inoculum as a form of vaccination. The biggest issue with this, as I understand, is straddling the line between causing an immune response and hurting the patient. There are live vaccine viruses, but most (all?) attenuate the virus to prevent the latter.