But it's hard to not get inspiration from the real world, isn't it? How much would the writers have to change before the movie was no longer about Amanda Knox?

But it's hard to not get inspiration from the real world, isn't it? How much would the writers have to change before the movie was no longer about Amanda Knox? Would it be sufficient to change her gender? What if it took place in the nineteenth century, or in a Game of Thrones-esque fantasy universe? Or would it all be for naught as soon as a reporter asked the right interview question?