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I guess they're expecting the vaccine to, you know, confer immunity? Like how nearly every vaccine except the mRNA ones do Maybe they're expecting the vaccine

I guess they're expecting the vaccine to, you know, confer immunity? Like how nearly every vaccine except the mRNA ones do Maybe they're expecting the vaccine to stop the transmission of the virus to others? Like how nearly every vaccine except the mRNA ones do

TillE 5y ago
No vaccine has ever conferred absolute immunity to everyone. The covid mRNA vaccines are extremely effective, far superior to the alternatives (the US is very fortunate to have never approved AstraZeneca), so I have no idea why you'd mention them in particular.
- didjathinkmess 5y ago
  "The delta variant is now the dominant strain of SARS-CoV-2 in Israel, where researchers now estimate that the two-shot Pfizer vaccine is only 39% effective in preventing an infection within the country." Source: https://www.salon.com/2021/07/28/pfizer-vaccine-less-effectiveness-fluke/ https://www.salon.com/2021/07/28/pfizer-vaccine-less-effecti... Um yeah, they're great.
  - nojokes 5y ago
    It is not well known how many doses we need to get near full immunity. Some other vaccines require up to 3 doses https://www.cdc.gov/vaccines/schedules/hcp/imz/adult.html https://www.cdc.gov/vaccines/schedules/hcp/imz/adult.html
    - didjathinkmess 5y ago
      Sounds like goal post shifting honestly. The mRNA clinical trials were done with 2 doses. It was sold as 90%+ effective on the 200 people they studied (erroneously claimed as over 40,000 people but I digress - that's information for only detailed oriented people to discover). Now suddenly a 3rd is necessary? What happens when that fails, a second booster? A yearly vaccine like the flu shot (which barely works anyways)? Unfortunately for us humans, nature finds a way. Speaking of nature, you know what confers full immunity? Having the infection and then recovering or having cross reactive immunity from a previous coronavirus strain. Natural immunity is the undisputed champion of immunity.
      - nojokes 5y ago
        Remember, these vaccines were developed for the original variant, goal post have not been shifted. Reality is. Nobody imagined that r0 would grow from 2.5 to 6.4 in such short time. Even infection does not give full immunity but so far it appears to be better than vaccines. Besides it comes with very heavy cost without vaccination. With vaccination it might be possible without heavy losses.
nojokes 5y ago
You mean like adenovirus vector vaccines do or inactivated virus Sinovac? There is nothing to do with mRNA vaccines here.

TillE 5y ago

No vaccine has ever conferred absolute immunity to everyone. The covid mRNA vaccines are extremely effective, far superior to the alternatives (the US is very fortunate to have never approved AstraZeneca), so I have no idea why you'd mention them in particular.

didjathinkmess 5y ago
"The delta variant is now the dominant strain of SARS-CoV-2 in Israel, where researchers now estimate that the two-shot Pfizer vaccine is only 39% effective in preventing an infection within the country." Source: https://www.salon.com/2021/07/28/pfizer-vaccine-less-effectiveness-fluke/ https://www.salon.com/2021/07/28/pfizer-vaccine-less-effecti... Um yeah, they're great.
- nojokes 5y ago
  It is not well known how many doses we need to get near full immunity. Some other vaccines require up to 3 doses https://www.cdc.gov/vaccines/schedules/hcp/imz/adult.html https://www.cdc.gov/vaccines/schedules/hcp/imz/adult.html
  - didjathinkmess 5y ago
    Sounds like goal post shifting honestly. The mRNA clinical trials were done with 2 doses. It was sold as 90%+ effective on the 200 people they studied (erroneously claimed as over 40,000 people but I digress - that's information for only detailed oriented people to discover). Now suddenly a 3rd is necessary? What happens when that fails, a second booster? A yearly vaccine like the flu shot (which barely works anyways)? Unfortunately for us humans, nature finds a way. Speaking of nature, you know what confers full immunity? Having the infection and then recovering or having cross reactive immunity from a previous coronavirus strain. Natural immunity is the undisputed champion of immunity.
    - nojokes 5y ago
      Remember, these vaccines were developed for the original variant, goal post have not been shifted. Reality is. Nobody imagined that r0 would grow from 2.5 to 6.4 in such short time. Even infection does not give full immunity but so far it appears to be better than vaccines. Besides it comes with very heavy cost without vaccination. With vaccination it might be possible without heavy losses.

nojokes 5y ago

You mean like adenovirus vector vaccines do or inactivated virus Sinovac? There is nothing to do with mRNA vaccines here.