Aside from the issue of box-office split I imagine like there are a lot of other material ways actors lose out when this happens. A studio may look at a 50M ad

Aside from the issue of box-office split I imagine like there are a lot of other material ways actors lose out when this happens. A studio may look at a 50M ad buy and think that, because it would only net 60M in ticket sales tops, its not worth the risk. However, from the POV of the actor part of the reason they appeared in a big budget movie was to get lots of screentime on tv/ads beforehand to boost their profile.