I'm not a biologist, so this is my rough understanding. ADE is antibody-dependent enhancement, a phenomenon that could occur when your body is exposed to a vir

I'm not a biologist, so this is my rough understanding. ADE is antibody-dependent enhancement, a phenomenon that could occur when your body is exposed to a virus for a second time. Normally, your body has developed antibodies and therefore can fight off the virus easily. However, if the second infection is a different serotype, then (in rare cases) the body's antibodies might actually help the second virus infect your body's cells and cause worse disease. Or, they don't properly neutralize the virus (and your body might not develop new antibodies). This has happened in the past with previous vaccines [1]. We know that ADE is a risk; therefore, we specifically designed Covid animal trials to look for ADE events [2]. Also, we monitored for ADE events during human trials. There hasn't been a single confirmed case of ADE to my knowledge. That hasn't stopped antivaxxers from using ADE fears to claim that the currently approved Covid vaccines aren't safe. [1] https://www.chop.edu/centers-programs/vaccine-education-center/vaccine-safety/antibody-dependent-enhancement-and-vaccines https://www.chop.edu/centers-programs/vaccine-education-cent... [2] https://blogs.sciencemag.org/pipeline/archives/2021/02/12/antibody-dependent-enhancement-and-the-coronavirus-vaccines https://blogs.sciencemag.org/pipeline/archives/2021/02/12/an...