4 ms·
All strong antivirals are likely to have some side effects. Almost every medical intervention has effects, the most common of which is a lighter wallet. I sup
by OrvalWintermute 5y ago
All strong antivirals are likely to have some side effects. Almost every medical intervention has effects, the most common of which is a lighter wallet.
I support Remdesivir/Veklury which is a potent IV antiviral. Likewise, it has the following side effects
Hypersensitivity Including Infusion-Related and Anaphylactic Reactions
Hypersensitivity reactions, including infusion-related and anaphylactic reactions,
have been observed during and following administration of VEKLURY. Signs and
symptoms may include hypotension, hypertension, tachycardia, bradycardia,
hypoxia, fever, dyspnea, wheezing, angioedema, rash, nausea, diaphoresis, and
shivering. Slower infusion rates, with a maximum infusion time of up to 120
minutes, can be considered to potentially prevent these signs and symptoms.
Monitor patients under close medical supervision for hypersensitivity reactions
during and following administration of VEKLURY. If signs and symptoms of a
clinically significant hypersensitivity reaction occur, immediately discontinue
administration of VEKLURY and initiate appropriate treatment. The use of
VEKLURY is contraindicated in patients with known hypersensitivity to VEKLURY
or any components of the product
Increased Risk of Transaminase Elevations
Transaminase elevations have been observed in healthy volunteers who
received 200 mg of VEKLURY followed by 100 mg doses up to 10 days; the
transaminase elevations were mild (Grade 1) to moderate (Grade 2) in severity
and resolved upon discontinuation of VEKLURY. Transaminase elevations have
also been reported in patients with COVID-19 who received VEKLURY. Because
transaminase elevations have been reported as a clinical feature of COVID-19,
and the incidence was similar in patients receiving placebo versus VEKLURY in
clinical trials of VEKLURY, discerning the contribution of VEKLURY to
transaminase elevations in patients with COVID-19 can be challenging