4 ms·

I'm not sure how you could be so skeptical after reading case report 4. Sure low sample size blah blah blah, but case report 4 had isolated her issues to MCA so

by ceedan 5y ago

I'm not sure how you could be so skeptical after reading case report 4. Sure low sample size blah blah blah, but case report 4 had isolated her issues to MCA so precisely, that it seems to validate the hypothesis. - 43 years old, raw food diet, never/rarely consumed MCA. - Started to drink water w/ vitamin c powder and had bad reactions for 2 years. - Stopped drinking the vitamin c mixture she was drinking, and her symptoms went away - Tried ANOTHER vitamin c mixture without MCA, and she has NO symptoms. Paragraph 1 of the Conclusion: > We recognize the limitations of the level of evidence from our four case reports. We cannot conclusively affirm that MCA is the causative factor in the subjects’ inflammatory symptoms. However, our findings demonstrate a significant likelihood that MCA may be the culprit and are suggestive of valid concerns which warrant proper double blind studies to determine presence or absence of harm.

harles 5y ago
Self isolated and self reported improvements. Where did these studies come from? Relying on self reported anecdotes seems pretty far from science. Maybe it’s normal as a starting point - but it strikes me as the sort of bias science aims to weed out. Compelling well written anecdotes are still anecdotes.
- ceedan 5y ago
  You're being overly critical of a scientific article that is very aware of its statistical limitations. I would also venture to guess that you've never suffered from or attempted to self diagnose a chronic health issue. The people in this article had been suffering for years (case 1 was possible 10+ years) and each went through a pretty scientific process of food elimination. To suggest that this might be a placebo effect is ridiculous. Cases 1, 2 and 3 all mention a reocurrence of symptoms after consuming MCA - unlikely that these people are dealing with repeated placebo effect that happens to occur after eating MCA.
  - harles 5y ago
    Again self reported. There are no statistical limits on a story which may or may not be true and has no control over outside factors. This simply isn’t science - it’s a reasonable place to start for a hypothesis, but it’s not science. This is how we end up with chiropractors and acupuncture.

by ceedan 5y ago

harles 5y ago

Self isolated and self reported improvements. Where did these studies come from? Relying on self reported anecdotes seems pretty far from science. Maybe it’s normal as a starting point - but it strikes me as the sort of bias science aims to weed out. Compelling well written anecdotes are still anecdotes.

ceedan 5y ago
You're being overly critical of a scientific article that is very aware of its statistical limitations. I would also venture to guess that you've never suffered from or attempted to self diagnose a chronic health issue. The people in this article had been suffering for years (case 1 was possible 10+ years) and each went through a pretty scientific process of food elimination. To suggest that this might be a placebo effect is ridiculous. Cases 1, 2 and 3 all mention a reocurrence of symptoms after consuming MCA - unlikely that these people are dealing with repeated placebo effect that happens to occur after eating MCA.
- harles 5y ago
  Again self reported. There are no statistical limits on a story which may or may not be true and has no control over outside factors. This simply isn’t science - it’s a reasonable place to start for a hypothesis, but it’s not science. This is how we end up with chiropractors and acupuncture.