4 ms·
> It's from the lack of heavy metals - lead is necessary for transporting glucose to the axon, and its deficiency leads to massive synapse loss and resulting me
by ashleyn 5y ago
> It's from the lack of heavy metals - lead is necessary for transporting glucose to the axon, and its deficiency leads to massive synapse loss and resulting mental illness.
I'm going to need a reference for this because I was under the impression that there is no safe level for lead in the body, and it serves no biological purpose.
- Gauge_Irrahphe 5y agohttps://www.sciencedirect.com/science/article/abs/pii/S0378427419300967 https://www.sciencedirect.com/science/article/abs/pii/S03784...
- ad 5y agoI can't download the paper. I'm sorry, but reading the abstract, I don't see how that paper supports your argument. "Highlights • Chronic Pb exposure could result in a lower weight gain in rats and a higher Pb content in the brain of model rats. • Pb exposure reduced activities of key enzymes of glucose metabolism in the brain. • Pb exposure could disrupt the insulin signaling pathway in the hippocampus of rats."
- Gauge_Irrahphe 5y agoLower insulin is good. Some of these proteins are targeted by Rapamycin. The glucose transports are increased, (GLUT3 is the one that supplies axons) and the rats weighed less.