After two doses, overall T cell levels were 1.6 times lower after the long compared with the short dosing schedule. However, after the longer dosing interval, a

After two doses, overall T cell levels were 1.6 times lower after the long compared with the short dosing schedule. However, after the longer dosing interval, a higher proportion of T cells present were ‘helper’ T cells, which are important for long-term immune memory and helping generate antibodies to prevent infection. The data I'd like to see discovered is if and when this effect tapers off. Surely we need that to know the optimal time to take a booster? (This is assuming the vaccine makeup hadn't changed and you're not taking a booster to immunize against variants.)