On the other hand, caffeine is a vaso-constrictor which reduces blood supply to the brain. This is very old news and replicated many times from even 1935. What

On the other hand, caffeine is a vaso-constrictor which reduces blood supply to the brain. This is very old news and replicated many times from even 1935. What are the effects of this? To go full forward we have https://www.biorxiv.org/content/10.1101/2021.07.01.450708v1.full.pdf https://www.biorxiv.org/content/10.1101/2021.07.01.450708v1.... (July 2 2021) "Our findings unveil that conventional daily caffeine intake does not provide sufficient time to clear up psychoactive compounds and restore cerebral responses, even after 36 hours of abstinence. They also suggest investigating consequences of a paraxanthine accumulation during daily caffeine intake." As an avid coffee drinker I'd like to feel able to agree with your conclusion but I'll limit the amount wagered. https://pubmed.ncbi.nlm.nih.gov/19219847/ https://pubmed.ncbi.nlm.nih.gov/19219847/ Coffee has a lot of other components such as polyphenols which generally have a beneficial effect. May be that this counteracts the possible negative consequences of caffeine under certain conditions.