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In addition, the vaccines currently in use -- at least in the West -- are either mRNA or vector vaccines containing only parts of the virus (as far as I know on

In addition, the vaccines currently in use -- at least in the West -- are either mRNA or vector vaccines containing only parts of the virus (as far as I know only the spike protein from the virus's surface). I would expect them to result in a more specific immunity which is easier for the virus to circumvent, my mutating only its spike protein. Conventional vaccines however, which are more prevalent in the developing world, as well as having gone through COVID, should provide a broader immunity - at least in my half-educated view.

Pyramus 5y ago
> I would expect them to result in a more specific immunity which is easier for the virus to circumvent, my mutating only its spike protein. This is not clear at all - actually the opposite might be the case. Natural immunity focuses on a number of 'markers' that are more likely to change than the spike protein. As far as I know we don't know yet. Here is a comparison with other vaccines [1]. [1] https://twitter.com/ENirenberg/status/1412865782862725125 https://twitter.com/ENirenberg/status/1412865782862725125
becuzThrowaway 5y ago
My guess is that nobody really knows the answer to that question. It's also entirely plausible that the only way to have true sterilizing immunity to COVID is to have antibodies to the spike protein. shrugs