3 ms·

They have emergency approval. All major studies are completed, Clinical Study Reports are submitted with all evidence, Case Report Forms, datasets. It is import

They have emergency approval. All major studies are completed, Clinical Study Reports are submitted with all evidence, Case Report Forms, datasets. It is important but largely a bureaucratic and scientific exercise at this point. These vaccines are safer and more effective, with less side effects, than the bulk of all medicines submitted last year. People have been working around the clock for the last 18 months on these treatments in an attempt to save more lives. If the propagandists cared a whit about humanity they would encourage everybody to vaccinate immediately. It is quite possible that a variant will be created by the unvaccinated that is resistant to the vaccines, one that is perhaps even more deadly, instantly turning the world back to lockdown for another year.

HdiJWQCycmpbGd 5y ago
The COVID-19 vaccines are all "leaky" in that they don't really prevent infection and transmission but simply attenuate and reduce the severity of symptoms. Therefore, Sars-Cov-2 will continue to evolve in both unvaccinated and vaccinated populations, but the vaccine will put evolutionary pressure on Sars-Cov-2 in the vaccinated population that will select for fitter variants (this has happened before in other "leaky" vaccines, see: https://en.wikipedia.org/wiki/Marek%27s_disease#Prevention https://en.wikipedia.org/wiki/Marek%27s_disease#Prevention and https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002198 https://journals.plos.org/plosbiology/article?id=10.1371/jou...). I'd argue that fitter, more dangerous variants will probably evolve in the vaccinated population as opposed to the unvaccinated for this reason. Having said that, these new variants will mostly be a threat to the unvaccinated and, if so, I can see a future where we'll be vaccinating kids very early on to prevent serious disease.
- jaybrendansmith 5y ago
  While I hear what you're saying, were we all vaccinated, we would quickly reach herd immunity and the virus would stop bouncing around completely, thus rendered a historical footnote like Polio and Smallpox.

HdiJWQCycmpbGd 5y ago

The COVID-19 vaccines are all "leaky" in that they don't really prevent infection and transmission but simply attenuate and reduce the severity of symptoms. Therefore, Sars-Cov-2 will continue to evolve in both unvaccinated and vaccinated populations, but the vaccine will put evolutionary pressure on Sars-Cov-2 in the vaccinated population that will select for fitter variants (this has happened before in other "leaky" vaccines, see: https://en.wikipedia.org/wiki/Marek%27s_disease#Prevention https://en.wikipedia.org/wiki/Marek%27s_disease#Prevention and https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002198 https://journals.plos.org/plosbiology/article?id=10.1371/jou...). I'd argue that fitter, more dangerous variants will probably evolve in the vaccinated population as opposed to the unvaccinated for this reason. Having said that, these new variants will mostly be a threat to the unvaccinated and, if so, I can see a future where we'll be vaccinating kids very early on to prevent serious disease.

jaybrendansmith 5y ago
While I hear what you're saying, were we all vaccinated, we would quickly reach herd immunity and the virus would stop bouncing around completely, thus rendered a historical footnote like Polio and Smallpox.