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There's this study published in Diabetes Care[1], "Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients Wi
by mullingitover 5y ago
There's this study published in Diabetes Care[1], "Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study".
> RESULTS Compared with placebo, THCV significantly decreased fasting plasma glucose (estimated treatment difference [ETD] = −1.2 mmol/L; P < 0.05) and improved pancreatic β-cell function (HOMA2 β-cell function [ETD = −44.51 points; P < 0.01]), adiponectin (ETD = −5.9 × 106 pg/mL; P < 0.01), and apolipoprotein A (ETD = −6.02 μmol/L; P < 0.05), although plasma HDL was unaffected. Compared with baseline (but not placebo), CBD decreased resistin (−898 pg/ml; P < 0.05) and increased glucose-dependent insulinotropic peptide (21.9 pg/ml; P < 0.05). None of the combination treatments had a significant impact on end points. CBD and THCV were well tolerated.
[1] https://care.diabetesjournals.org/content/39/10/1777.long https://care.diabetesjournals.org/content/39/10/1777.long
- code_duck 5y agoIn the case of type 2 diabetes patients, reducing fasting plasma glucose is exactly what you would want to do since chronic hyperglycemia is the major issue in that condition. It’s not clear if it would work the same for type 1 or non-diabetic people.